Release date: June 1, 2009
Expiration date: June 1, 2010
NEW CME Activity discussing the important aspects of drug resistance in chronic hepatitis B

THE RESISTANCE REVOLUTION:
Prevention and Management of Resistance in Patients With Chronic Hepatitis B

SCIENTIFIC AGENDA
•
What is Resistance and How Do We Find It?
•
Current Therapeutic Options in HBV
•
Preventing Resistance by Using Combination Therapy

EDUCATIONAL OBJECTIVES
After completing this activity, participants will be better able to:
•
Describe the mechanisms for development of resistance during treatment of CHB
•Discuss methods for monitoring and detecting development of resistance
•
Compare resistance profiles of current and novel agents for the treatment of CHB
•
Articulate the clinical consequences of resistance and develop strategies for managing patients with drug-resistant HBV

TARGET AUDIENCE
This activity has been designed to meet the educational needs of physicians and physician assistants involved in the care of patients with chronic hepatitis B (CHB).

ACCREDITATION
 This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the University of Kentucky College of Medicine and HealthmattersCME.

The University of Kentucky College of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of Kentucky College of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The University of Kentucky College of Medicine presents this activity for educational purposes only. Participants are expected to utilize their own expertise and judgment while engaged in the practice of medicine. The content of the presentations is provided solely by faculty who have been selected because of recognized expertise in their field.


STATEMENT OF DISCLOSURE
 All faculty members participating in continuing medical education programs sponsored by the University of Kentucky College of Medicine are expected to disclose any real or perceived conflict of interest related to the content of the publications.

The University of Kentucky is an Equal Opportunity University.

This program is supported by an
independent educational grant from Gilead Sciences Medical Affairs.
This activity is jointly sponsored by the University of Kentucky College
of Medicine and HealthmattersCME.

Moderator

ROBERT S. BROWN, Jr, MD, MPH
Frank Cardile Professor of Medicine and Surgery
Chief, Division of Abdominal Organ Transplantation
Columbia University College of Physicians & Surgeons
New York Presbyterian Hospital
New York, NY

Faculty

STEVEN L. FLAMM, MD
Professor, Division of Hepatology Northwestern University
Feinberg School of Medicine
Chicago, IL

TRAM T. TRAN, MD
Assistant Professor of Medicine
Geffen UCLA School of Medicine Division of Gastroenterology
Medical Director, Liver Transplantation
Comprehensive Transplant Center
Cedars-Sinai Medical Center
Los Angeles, CA

FINANCIAL DISCLOSURES

Robert S. Brown, Jr, MD, MPH

• Grant/Research Support: Gilead Sciences, Inc, Roche, Schering-Plough

Steven L. Flamm, MD

• Speakers Bureau: Gilead Sciences, Inc.
• Grant/Research Support: Gilead Sciences, Inc.
• Consultant: Gilead Sciences, Inc.

Tram T. Tran, MD

• Grant/Research Support: Bristol-Myers Squibb, Gilead Sciences, Inc.
• Consultant: Bristol-Myers Squibb, Gilead Sciences, Inc.