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IAS 2015: Fibrosis Regression Linked to Reduced Complications and Death in HIV/HCV Coinfected

HIV/HCV coinfected people with cirrhosis who achieve sustained virological response (SVR) and experience an improvement in liver fibrosis are less likely to develop liver disease complications or die from liver-related causes -- and in some cases fibrosis regression is beneficial even in the absence of a cure -- according to a presentation at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last week in Vancouver. A related study looked at predictors of liver fibrosis progression in HIV/HCV coinfected people, finding that use of certain NRTI "backbone"' antiretroviral drugs and HIV protease inhibitors may increase the risk.

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