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EASL 2012: Telbivudine Effective for Hepatitis B Patients Selected with Roadmap

Telbivudine (Tyzeka) is an effective treatment for chronic hepatitis B with minimal emergence of drug resistance when using the "Roadmap" algorithm for selecting appropriate patients and deciding when to add other agents, according to a trio of studies presented at the 47th International Liver Congress (EASL 2012) last month in Barcelona.alt

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EASL 2012: Having Only Wild-type Hepatitis B Virus Predicts Response to Interferon

Chronic hepatitis B patients who do not have 2 common HBV mutations are more likely to achieve undetectable viral load and HBsAg loss when treated with pegylated interferon, according to study findings presented at the 47th International Liver Congress (EASL 2012) last month in Barcelona.alt

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Canadian Researchers Make Progress in Quest for Hepatitis C Vaccine

Researchers at the University of Albert say they have discovered a new vaccine candidate that stimulates immune response against all genotypes of hepatitis C virus (HCV). The variability of the virus enables it to elude the immune system and has so far hampered efforts to develop an effective vaccine.alt

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Scientists Find Antibodies that Neutralize Multiple Strains of Hepatitis C Virus

As described in a report published in the April 4, 2012, online edition of Proceedings of the National Academy of Sciences, Erick Giang and Mansun Law from the Scripps Research Institute and colleagues have identified a set of antibodies with activity against 5 different antigenic regions on the E1E2 complex of the hepatitis C virus (HCV) outer envelope.alt

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Experimental Hepatitis C Vaccine Triggers T-Cell Responses in Early Clinical Trial

An investigational adenovirus-based hepatitis C virus (HCV) vaccine induced sustained T-cell responses and cytokine production in a small Phase 1 study of healthy volunteers, according to findings reported in the January 4, 2012, issue of Science Translational Medicine.alt

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