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AIDS2014: Efavirenz Use Not Linked to Neurocognitive Impairment, Study Finds

People who use antiretroviral regimens containing efavirenz (Sustiva, also in the Atripla coformulation) were not at higher risk for impaired neurocognitive function, either overall or when looking at specific functional domain, researchers reported this week at the 20th International AIDS Conference in Melbourne, Australia.

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AIDS 2014: Weight Gain on ART May Raise Risk of Heart Disease and Diabetes

People with HIV who gain weight shortly after starting antiretroviral therapy (ART) may have an increased risk of cardiovascular disease and diabetes, according to findings from the D:A:D study presented this week at the 20th International AIDS Conference in Melbourne, Australia.

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People with HIV Are at Higher Risk for Cancers Linked to Smoking, Viruses

People with HIV appeared to have a higher overall rate of cancer in a large Danish study, but the difference was only significant for malignancies caused by smoking or other viruses, including lung cancer, anal cancer, and liver cancer. A related U.S. study found the rate of prostate cancer was actually lower among HIV positive men.

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Coverage of the 2014 International AIDS Conference

HIVandHepatitis.com coverage of the 20th International AIDS Conference (AIDS 2014), July 20-25, in Melbourne, Australia.

Conference highlights include biomedical HIV prevention (PrEP and treatment-as-prevention), HIV cure research, interferon-free therapy for hepatitis C and HIV/HCV coinfection, access to treatment, and fighting stigma and criminalization of key affected populations.

Full listing by topic

7/25/14

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ASCO: HCV Reactivation, Brain Involvement Do Not Worsen Lymphoma Survival for People with HIV

Reactivation of hepatitis C was common among HIV positive people with lymphoma, but did not appear to lead to worse outcomes or decreased survival, according to a study presented at the 50th American Society of Clinical Oncology (ASCO) meeting this week in Chicago. A related study found that having central nervous system involvement at the time of diagnosis did not decrease survival of people with AIDS-related lymphoma.

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AIDS 2014: Anal Lesions Often Resolve Without Treatment In HIV Positive Gay Men

High-grade anal dysplasia is common among gay men living with HIV, but it often resolves spontaneously and routine treatment may not be beneficial, according to results from the Australian SPANC study presented this week at the 20th International AIDS Conference in Melbourne.

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Rilpivirine Is Associated with Less Blood Fat Elevation than Efavirenz

People with HIV who started first-line treatment with a regimen containing rilpivirine (Edurant, also in the Complera coformulation) had smaller blood lipid increases and were less likely to have abnormal levels than those who started on efavirenz (Sustiva, also in the Atripla coformulation), according to 2-year data from the ECHO and THRIVE trials published in the April 11 online edition of Clinical Infectious Diseases.

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ASCO: Characteristics and Disparities of Care for HIV+ People with Lung Cancer

HIV positive people with lung cancer are diagnosed at a younger age and have shorter survival than HIV negative people, on average, suggesting that screening should perhaps be started earlier, according to studies presented at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) this month in Chicago.

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People with HIV Have Higher Bone Fracture Risk in Danish Study

Being HIV positive was associated with a nearly 3-fold greater likelihood of bone fractures overall -- and a 9-fold higher risk of hip and spine fractures -- compared with HIV negative people, according to results from a large Danish population study described in the May 1 Journal of Acquired Immune Deficiency Syndromes.

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