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HIV / AIDS

Semen May Enhance HIV Infectivity and Impair Microbicide Effectiveness

A component in semen appears to increase the likelihood of sexual transmission of HIV, and furthermore may enable the virus to over-power topical microbicides designed to prevent infection, according to a study published in the November 12 edition of Science Translational Medicine. This may be one of the factors explaining why drugs that block HIV infection in laboratory experiments have not worked in real-world settings, the researchers suggested.

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European Commission Approves Boosted Darunavir Combo Rezolsta for HIV

The European Commission last month approved a new fixed-dose coformulation -- dubbed Rezolsta -- containing the HIV protease inhibitor darunavir boosted with the novel pharmacoenhancer cobicistat, Janssen recently announced. The combination is currently being evaluated for U.S. approval.

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UNAIDS: HIV Epidemic Will Spring Back without Near-Universal Diagnosis and Treatment

Adopting "fast-track" targets could avert more than 28 million new HIV infections and prevent 21 million AIDS-related deaths by 2030, according to this year's UNAIDS World AIDS Day Report. However, if the response is not rapidly scaled-up over the next 5 years to achieve near-universal diagnosis and treatment, the epidemic is likely to "spring back" with an even higher rate of new HIV infections than today, the report warns.

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Only 30% of People with HIV in U.S. Have Undetectable Viral Load

Less than one-third of people living with HIV in the U.S. are on antiretroviral therapy (ART) with full viral suppression, which is key to good health and reduced risk of transmission, according to the latest CDC Vital Signs report. In 2011, out of an estimated 1.2 million people living with HIV, just 4 in 10 were receiving HIV medical care and only 3 in 10 had undetectable viral load. "The bottom line is HIV care and treatment not only work to improve health and prolong lives, but also prevent transmission," said CDC director Tom Frieden. "You can save your life and save the life of someone else."

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December 1 Is World AIDS Day

Monday, December 1, is the 26th World AIDS Day, an opportunity both to remember the millions of people who have been lost to the epidemic and to raise awareness and focus efforts on ongoing challenges such as gaps in HIV prevention and care. An estimated 1.2 million people in the U.S. and 35 million worldwide are now living with HIV/AIDS, according to the CDC.

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CDC Surveillance Report Shows Small Decline in HIV Diagnosis, but Disparities Persist

While the overall number of new HIV infections remains stable, the rate of diagnosis appears to be decreasing, according to the latest HIV Surveillance Report from the U.S. Centers for Disease Control and Prevention (CDC), which includes data through the end of 2012. Black and Latino people, men who have sex with men, and young people continue to be disproportionately affected by the HIV/AIDS epidemic.

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PLoS Publishes Free Special Collection on HIV Care and Prevention for Sex Workers

PLoS, publisher of open-access research, has announced a special collection of articles on the health of female sex workers, focusing on delivery and scale-up of HIV care and prevention interventions. UNAIDS and other organizations have recognized sex workers as of the key affected populations in the HIV/AIDS epidemic.

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