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HIV/AIDS Epidemiology & Mortality

HIV Prevalence and New Infections Highest Among Gay Men in Southern U.S.

The burden of HIV in the U.S. is disproportionately high for gay and bisexual men -- who account for about two-thirds of all newly diagnosed infections each year -- and HIV prevalence and new infections among men who have sex with men (MSM) is highest in states in the southeast, according to a new analysis published recently in the Journal of Medical and Internet Research -- Public Health and Surveillance.

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U.S. On Course to End Its HIV Epidemic -- Eventually

If current trends continue, the U.S. may eventually end its HIV epidemic, a mathematical model recently published in AIDS and Behavior shows. In 2009, the average number of people each person with HIV would infect during their lifetime fell below 1, and has now declined to 0.75, the model shows. This means the number of people living with HIV will eventually start to shrink, as more aging HIV-positive people start to die than new people getting infected. For the moment, however, since mortality among people with HIV also continues to fall, the number of people living with the virus continues to grow slowly.

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CROI 2016: Life Expectancy of HIV-Positive People in U.S. Still Lags 13 Years Behind HIV-Negatives

A study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) comparing life expectancies of HIV-positive and HIV-negative people within the Kaiser Permanente health system has found that although life expectancy among HIV-positive people has improved, expected life at age 20 remains 13 years behind that of matched HIV-negative people. This 13-year gap did not improve between 2008 and 2011, the last year of follow-up in this cohort study.

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Model Suggests There Are Fewer People with HIV in U.S. and More on Treatment

A study comparing recorded diagnoses of HIV with subsequent records of viral load and CD4 T-cell tests suggests that the number of people living with HIV in the U.S. could have been overestimated by as much as 45% -- and the proportion who are on antiretroviral therapy (ART) with undetectable viral loads could have been underestimated by as much as 50%. There could be as few as 820,000 people with HIV in the U.S. compared with the normally accepted figure of 1.2 million -- and up to 55% of those could be on ART and virally suppressed, compared with the most commonly quoted figure of 30%.

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CROI 2016: Major Disparities Persist in Lifetime Risk of HIV Diagnosis in the U.S.

The lifetime risk of being diagnosed with HIV infection in the U.S. has decreased overall during the past decade, falling to 1 in 99, according to a study from the Centers for Disease Control and Prevention (CDC) presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016)this week in Boston. The risk varies widely among population subgroups, however, and half of black gay and bisexual men are likely to become infected if current trends persist.

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