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Pre-exposure Prophylaxis (PrEP)

ASM Microbe 2016: PrEP Use Is Rising Fast in U.S., But Large Racial Disparities Remain

More than 49,000 people in the U.S. have filled prescriptions for Truvada for pre-exposure prophylaxis (PrEP) at retail pharmacies, according to the results of a survey by Gilead Sciences presented this week at the ASM Microbe conference in Boston. Among PrEP users with available data, most were white gay men; black people used PrEP much less often, despite having the highest rates of HIV infection.

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At Least 6000 People Thought to Be on HIV PrEP in San Francisco

New numbers from the city's largest pre-exposure prophylaxis (PrEP) programs, along with estimates from primary providers and other smaller sources, suggest that more than 6000 people in San Francisco are receiving or have received Truvada for HIV prevention, most of them gay and bisexual men.

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CROI 2016: Dose-Finding Trials of Antibody-Based Drugs for HIV Prevention To Start Soon

The next generation of pre-exposure prophylaxis (PrEP), and even HIV treatment, may consist of antibodies that could be given as an intravenous infusion or an injection into muscle, according to 2 presenters at the Conference on Retroviruses and Opportunistic Infections (CROI 2016)last month in Boston.

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BHIVA 2016: Which Men Stand to Benefit Most from PrEP?

New data from the PROUD pre-exposure prophylaxis (PrEP) study have identified the characteristics of the gay and other men who have sex with men who are most likely to benefit from PrEP, according to findings reported at the recent conference of the British HIV Association (BHIVA) in Manchester. Gay men with rectal sexually transmitted infections (STIs) and those who had unprotected receptive anal sex with more partners were most likely to benefit from PrEP.

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Study Sheds Light on Why Women Need More Truvada for HIV PrEP

Tenofovir and emtricitabine -- the drugs in the Truvada combination pill used for HIV pre-exposure prophylaxis (PrEP) -- reach higher levels in rectal compared with female genital tract tissue, and the rectum also contains fewer of the natural DNA building blocks that compete with the drugs, according to research published in the February 24 advance online edition of the Journal of Infectious Diseases.

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