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Pre-exposure Prophylaxis (PrEP)

CROI 2014: Tenofovir Alone May Work as Well as Truvada for Pre-exposure Prophylaxis

Tenofovir used as a single agent for pre-exposure prophylaxis (PrEP) may be as effective as the Truvada (tenofovir/emtricitabine) coformulation for preventing HIV infection, which, if confirmed, could have implications for cost and access worldwide.

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Truvada PrEP Did Not Cause Major Kidney Problems in HIV Prevention Trial

Gay men who used Truvada (tenofovir/emtricitabine) for HIV pre-exposure prophylaxis (PrEP) were unlikely to develop impaired kidney function in the iPrEx study, according to a report in the February 4 advance edition of AIDS. Creatinine clearance decreased slightly on average among Truvada recipients, but returned to normal after stopping PrEP.

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PrEP Does Not Promote Increased Sexual Risk Behavior among Gay Men

Using Truvada (tenofovir/emtricitabine) for pre-exposure prophylaxis (PrEP) to prevent HIV infection was not associated with an increase in sex without condoms and it appears to promote active engagement in risk reduction, according to a report in the December 18, 2013, edition of PLoS ONE.

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Most U.S. Providers Support PrEP, but Not Many Have Prescribed It

About three-quarters of infectious disease physicians in North America said they favored HIV pre-exposure prophylaxis (PrEP), but only 9% reported that they had prescribed Truvada (tenofovir/emtricitabine) for this purpose, according to a report in the December 6, 2013, advance edition of Clinical Infectious Diseases.

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San Francisco Forum Discusses Condomless Sex and HIV Prevention

A standing-room-only crowd packed the house at Magnet in San Francisco's Castro district on December 3 for a Real Talk discussion about condomless sex and HIV prevention. A panel of community members and medical experts considered questions such as: Why do gay and bisexual men have condom-free sex? Are community attitudes around condom use changing? and How do treatment as prevention and pre-exposure prophylaxis (PrEP) factor into the equation?

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