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Pre-exposure Prophylaxis (PrEP)

AIDS 2014: Good Adherence Seen in IPERGAY Study of Intermittent PrEP

The first results from the IPERGAY study, a trial of pre-exposure prophylaxis (PrEP) in gay men taking place in France and Quebec, Canada, appear to indicate excellent adherence to a novel "pre-and-post" intermittent PrEP strategy designed to save money and reduce time spent taking PrEP unnecessarily. The results were presented at the 20th International AIDS Conference this week in Melbourne, Australia.

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AIDS 2014: iPrEx OLE Confirms PrEP Works, but Many Don't Take It [VIDEO]

The open-label extension of the iPrEx study found that Truvada pre-exposure prophylaxis (PrEP) was highly The open-label extension of the iPrEx study found that Truvada pre-exposure prophylaxis (PrEP) was highly effective among gay men who took it regularly to prevent HIV, but many did not do so, researchers reported this week at the 20th International AIDS Conference in Melbourne.

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WHO Recommends Pre-Exposure Prophylaxis for Men Who Have Sex with Men

Gay and bisexual men who are at risk for HIV infection should consider using antiretroviral drugs for pre-exposure prophylaxis (PrEP), according to new guidelines from the World Health Organization (WHO), part of a set of recommendations for key populations affected by the HIV/AIDS epidemic.

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AIDS 2014: iPrEx OLE Shows PrEP Effectiveness Is 100% for Those Taking 4 or More Doses per Week

iPrEx OLE, the open-label extension of the iPrEx study of pre-exposure prophylaxis (PrEP), reported its main findings this week at the 20th International AIDS Conference in Melbourne, Australia, published simultaneously in The Lancet Infectious Diseases. Overall PrEP effectiveness was 50% overall, but 100% in those taking 4 or more doses per week. There was a substantial early drop-out rate, especially among young people.

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New Studies Offer More Insight on HIV Sexual Transmission and Prevention

A new estimate puts the likelihood of HIV transmission via receptive anal sex at 138 per 10,000 acts, but looking at probabilities over a longer period provides a better understanding of risk than per-act probabilities, according to a pair of studies in the May 6 advance online edition of AIDS. Mathematical models showed that combining prevention methods -- especially those that include antiretroviral treatment-as-prevention or PrEP -- can greatly reduce the risk of transmission.

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